Institutions of the University of Bayreuth
Chair Organic Chemistry I - Univ.-Prof. Dr. Rainer Schobert

2022

Köhler, Leonhard H. F. ; Reich, Sebastian ; Begemann, Gerrit ; Schobert, Rainer ; Biersack, Bernhard:
2-Amino-4-aryl-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitriles with Microtubule-Disruptive, Centrosome-Declustering, and Antiangiogenic Effects in vitro and in vivo.
In: ChemMedChem. Vol. 17 (2022) Issue 10 . - No. e202200064.
ISSN 1860-7187
DOI der Verlagsversion: https://doi.org/10.1002/cmdc.202200064

Schott, Dorothea Sonja:
Clinical relevance of circulating epithelial tumor cells (CETCs) and circulating cancer stem cells (cCSCs) during different therapies of breast cancer patients.
Bayreuth , 2022 . - X, 177 P.
( Doctoral thesis, 2022 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Bär, Alexander:
Entwicklung flexibler Synthesestrategien für bioaktive Sphingolipide.
Bayreuth , 2022 . - X, 157 P.
( Doctoral thesis, 2022 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Soliga, Kevin:
Neue Synthesewege zu den natürlichen, diglykosidischen 3-Acyltetramsäuren Ancorinosid B und Ancorinosid C.
Bayreuth , 2022 . - X, 191 P.
( Doctoral thesis, 2022 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Bodenschatz, Kevin:
Neue synthetische Wege zu natürlichen 3-Enoyltetramsäuren und 5/5/6-polyzyklischen Tetramatmakrolactamen des Discodermid-Typs.
Bayreuth , 2022 . - IX, 178 P.
( Doctoral thesis, 2022 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Koko, Waleed S. ; Al Nasr, Ibrahim S. ; Khan, Tariq A. ; Schobert, Rainer ; Biersack, Bernhard:
An Update on Natural Antileishmanial Treatment Options from Plants, Fungi and Algae.
In: Chemistry & Biodiversity. Vol. 19 (2022) Issue 1 . - No. e202100542.
ISSN 1612-1880
DOI der Verlagsversion: https://doi.org/10.1002/cbdv.202100542

2021

Khan, Tariq A. ; Koko, Waleed S. ; Al Nasr, Ibrahim S. ; Schobert, Rainer ; Biersack, Bernhard:
Activity of Fluorinated Curcuminoids against Leishmania major and Toxoplasma gondii Parasites.
In: Chemistry & Biodiversity. Vol. 18 (2021) Issue 9 . - No. e2100381.
ISSN 1612-1880
DOI der Verlagsversion: https://doi.org/10.1002/cbdv.202100381

Gold, Madeleine:
Avoiding tumor resistance - different approaches for new chemotherapeutic agents and their mechanistic assessment.
Bayreuth , 2021 . - v, 262 P.
( Doctoral thesis, 2021 , University of Bayreuth, Bayreuther Graduiertenschule für Mathematik und Naturwissenschaften - BayNAT)

Kempf, Oxana ; Ullmann, G. Matthias ; Schobert, Rainer ; Kempf, Karl ; Bombarda, Elisa:
Chemoselective Attachment of the Water-Soluble Dark Quencher Hydrodabcyl to Amino Groups in Peptides and Preservation of Its Spectroscopic Properties over a Wide pH Range.
In: ACS Omega. Vol. 6 (2021) Issue 48 . - pp. 32896-32903.
ISSN 2470-1343
DOI der Verlagsversion: https://doi.org/10.1021/acsomega.1c04891

Treiber, Laura ; Pezolt, Christine ; Zeng, Haoxuan ; Schrey, Hedda ; Jungwirth, Stefan ; Shekhar, Aditya ; Stadler, Marc ; Bilitewski, Ursula ; Erb-Brinkmann, Maike ; Schobert, Rainer:
Dual Agents : Fungal Macrocidins and Synthetic Analogues with Herbicidal and Antibiofilm Activities.
In: Antibiotics. Vol. 10 (2021) Issue 8 . - No. 1022.
ISSN 2079-6382
DOI der Verlagsversion: https://doi.org/10.3390/antibiotics10081022

Corona, Angela ; Seibt, Sebastian ; Schaller, David ; Schobert, Rainer ; Volkamer, Andrea ; Biersack, Bernhard ; Tramontano, Enzo:
Garcinol from Garcinia indica inhibits HIV-1 reverse transcriptase-associated ribonuclease H.
In: Archiv der Pharmazie. Vol. 354 (2021) Issue 9 . - No. 2100123.
ISSN 1521-4184
DOI der Verlagsversion: https://doi.org/10.1002/ardp.202100123

Wunder, Anja Christina:
Neue Synthesewege zu hochfunktionalisierten bioaktiven Tetramsäuren : Caldoramid und JBIR-141/142.
Bayreuth , 2021 . - X, 210 P.
( Doctoral thesis, 2020 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Soliga, Kevin J. ; Bär, Sofia I. ; Oberhuber, Natalie ; Zeng, Haoxuan ; Schrey, Hedda ; Schobert, Rainer:
Synthesis and Bioactivity of Ancorinoside B, a Marine Diglycosyl Tetramic Acid.
In: Marine Drugs. Vol. 19 (2021) Issue 10 . - No. 583.
ISSN 1660-3397
DOI der Verlagsversion: https://doi.org/10.3390/md19100583

2020

Rothemund, Matthias:
Jenseits von Cisplatin : Aufklärung der intrazellulären Lokalisation und antitumoralen Wirkung neuer target-spezifischer Platinkomplexe mit N-heterozyklischen Carbenliganden.
Bayreuth , 2020 . - V, 190 P.
( Doctoral thesis, 2020 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Koko, Waleed S. ; Jentzsch, Jana ; Kalie, Hussein ; Schobert, Rainer ; Ersfeld, Klaus ; Al Nasr, Ibrahim S. ; Khan, Tariq A. ; Biersack, Bernhard:
Evaluation of the antiparasitic activities of imidazol-2-ylidene-gold(I) complexes.
In: Archiv der Pharmazie. Vol. 353 (2020) Issue 5 . - No. e1900363.
ISSN 1521-4184
DOI der Verlagsversion: https://doi.org/10.1002/ardp.201900363

Bär, Sofia I. ; Gold, Madeleine ; Schleser, Sebastian W. ; Rehm, Tobias ; Bär, Alexander ; Köhler, Leonhard ; Carnell, Lucas R. ; Biersack, Bernhard ; Schobert, Rainer:
Guided Antitumoural Drugs : (Imidazol-2-ylidene)(L)gold(I) Complexes Seeking Cellular Targets Controlled by the Nature of Ligand L.
In: Chemistry - a European Journal. Vol. 27 (2020) Issue 15 . - pp. 5003-5010.
ISSN 1521-3765
DOI der Verlagsversion: https://doi.org/10.1002/chem.202005451

Jentzsch, Jana ; Koko, Waleed S. ; Al Nasr, Ibrahim S. ; Khan, Tariq A. ; Schobert, Rainer ; Ersfeld, Klaus ; Biersack, Bernhard:
New Antiparasitic Bis-Naphthoquinone Derivatives.
In: Chemistry & Biodiversity. Vol. 17 (2020) Issue 2 . - No. e190059.
ISSN 1612-1880
DOI der Verlagsversion: https://doi.org/10.1002/cbdv.201900597

Rehm, Tobias:
Synthese und Wirkoptimierung antitumoraler Platinkomplexe mit N-heterozyklischen Carbenen.
2020 . - III, 180 P.
( Doctoral thesis, 2020 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

2019

Al Nasr, Ibrahim ; Jentzsch, Jana ; Winter, Isabel ; Schobert, Rainer ; Ersfeld, Klaus ; Koko, Waleed S. ; Mujawah, Adil A. H. ; Khan, Tariq A. ; Biersack, Bernhard:
Antiparasitic activities of new lawsone Mannich bases.
In: Archiv der Pharmazie. Vol. 352 (2019) Issue 11 . - No. 1900128.
ISSN 1521-4184
DOI der Verlagsversion: https://doi.org/10.1002/ardp.201900128

Schobert, Rainer ; Biersack, Bernhard:
Chemical and Biological Aspects of Garcinol and Isogarcinol : Recent Developments.
In: Chemistry & Biodiversity. Vol. 16 (2019) Issue 9 . - No. e190036.
ISSN 1612-1880
DOI der Verlagsversion: https://doi.org/10.1002/cbdv.201900366

Petermichl, Markus:
Flexible synthetische Zugänge zu bioaktiven O- und N-glykosylierten 3-Acyltetramsäuren aus Meeresschwämmen : Erstsynthese von Aurantosid G, Ancorinosid A und Methyl-Ancorinosid D.
Bayreuth , 2019 . - II, 209 P.
( Doctoral thesis, 2019 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Schwedes, Mathias:
Synthesis of organic pillar molecules and their application after intercalation into synthetic layered silicates.
Bayreuth , 2019 . - VI, 81 P.
( Doctoral thesis, 2019 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

2018

Bruckner, Sebastian:
Entwicklung flexibler Synthesestrategien zur Darstellung natürlicher, Tyrosin-abgeleiteter 3-Acyltetramsäuren - Die Synthesen von Torrubiellon D, F-14329, Militarinon C und Fumosorinon A.
2018 . - XII, 204 P.
( Doctoral thesis, 2018 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Schmidt, René C.:
Neuartige Makrocyclisierung von ω-Hydroxy-Hemiacetalen durch Ketenylidentriphenylphosphoran : Synthese chimärer Makrolid-Antibiotika.
Bayreuth , 2018 . - XXVI, 173 P.
( Doctoral thesis, 2018 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Linder, David:
Beiträge zur Chemie von 3-Acyltetron- und 3-Enamintetramsäuren : Erstsynthesen von (R)-(+)-Carolinsäure und Cladosin C.
Bayreuth , 2018 . - XIV, 163 P.
( Doctoral thesis, 2018 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Stöckl, Julia M.:
Modellstudien zur Entwicklung einer neuen Synthesemethode für polycyclische Tetramsäure-Makrolactame.
Bayreuth , 2018 . - XIV, 182 P.
( Doctoral thesis, 2018 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Kempf, Karl:
Synthese von 3-Acyltetramsäurederivaten und deren Markierung zur Visualisierung in Zellen.
Bayreuth , 2018 . - 200 P.
( Doctoral thesis, 2017 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

2017

Harras, Marina:
Neue Synthesen von Oxa[1.n]metaparacyclophanen der Combretastatin D Familie.
Bayreuth , 2017 . - 171 P.
( Doctoral thesis, 2016 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Winterer, Markus:
Beiträge zu den Totalsynthesen der natürlichen 3-Acyltetramsäuren Discodermid, Methiosetin und TA-289.
Bayreuth , 2017 . - 186 P.
( Doctoral thesis, 2017 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Haase, Robert:
Totalsynthese natürlicher, hochfunktionalisierter, Tyrosin-abgeleiteter 3-Acyl-Tetramsäuren - Macrocidin A und F-14329.
Bayreuth , 2017 . - VI, 143 P.
( Doctoral thesis, 2017 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

2016

Münzner, Julienne K.:
Biologische Evaluation der Wirkmechanismen neuartiger NHC-Metallkomplexe mit antitumoraler und antivaskulärer Aktivität.
Bayreuth , 2016 . - VII, 244 P.
( Doctoral thesis, 2016 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Schneider, Marc-André:
Synthese von Monoterpenen und Terpenendoperoxiden.
Bayreuth , 2016 . - 182 P.
( Doctoral thesis, 2016 , University of Bayreuth, Bayreuther Graduiertenschule für Mathematik und Naturwissenschaften - BayNAT)

2015

Spörlein-Güttler, Cornelia:
Komplexkonjugate bioaktiver Flavonoide & Naphthochinone und Photoaktivierung von Carboplatin für Studien der intrazellulären Verteilung.
Bayreuth , 2015 . - III, 203 P.
( Doctoral thesis, 2015 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Loscher, Sebastian:
Total synthesis of naturally occurring glycosylated tetramic acids.
Bayreuth , 2015 . - XI, 165 P.
( Doctoral thesis, 2015 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Kroscky, Anders:
Syntheses of natural bioactive 3-acyltetramic acids and derivatives.
Bayreuth , 2015 . - XIV, 311 P.
( Doctoral thesis, 2015 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

Seutter von Loetzen, Christian ; Jacob, Thessa ; Hartl-Spiegelhauer, Olivia ; Vogel, Lothar ; Schiller, Dirk ; Spörlein-Güttler, Cornelia ; Schobert, Rainer ; Vieths, Stefan ; Hartl, Maximilian J. ; Rösch, Paul:
Ligand Recognition of the Major Birch Pollen Allergen Bet v 1 is Isoform Dependent.
In: PLOS ONE. Vol. 10 (4 May 2015) Issue 6 . - e0128677.
ISSN 1932-6203
DOI der Verlagsversion: https://doi.org/10.1371/journal.pone.0128677

Ostermeier, Michael:
Entwicklung einer modularen Synthese chimärer Makrolidantibiotika aus Zuckern.
Bayreuth , 2015 . - 217 P.
( Doctoral thesis, 2015 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

2011

Zoldakova, Miroslava:
Biochemical studies of targeted and bimodal analogues of the natural anticancer compounds combretastatin A-4 and illudin M.
Bayreuth , 2011 . - VII, 145 P.
( Doctoral thesis, 2011 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)