Institutions of the University of Bayreuth
Chair Biochemistry - Univ.-Prof. Dr. Birte Höcker

2023

Kordes, Sina:
TIM Barrels 2.0 – Stabilizing and Diversifying a De Novo Designed Protein.
Bayreuth , 2023 . - ii, 190 P.
( Doctoral thesis, 2022 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

2022

Kordes, Sina ; Romero-Romero, Sergio ; Lutz, Leonie ; Höcker, Birte:
A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels.
In: Protein Science. Vol. 31 (2022) Issue 2 . - pp. 513-527.
ISSN 1469-896X
DOI der Verlagsversion: https://doi.org/10.1002/pro.4249

Ferruz, Noelia ; Schmidt, Steffen ; Höcker, Birte:
ProtGPT2 is a deep unsupervised language model for protein design.
In: Nature Communications. Vol. 13 (2022) Issue 1 . - No. 4348.
ISSN 2041-1723
DOI der Verlagsversion: https://doi.org/10.1038/s41467-022-32007-7

2021

Wiese, Jonas Gregor ; Shanmugaratnam, Sooruban ; Höcker, Birte:
Extension of a de novo TIM barrel with a rationally designed secondary structure element.
In: Protein Science. Vol. 30 (May 2021) Issue 5 . - pp. 982-989.
ISSN 1469-896X
DOI der Verlagsversion: https://doi.org/10.1002/pro.4064

Lechner, Horst ; Emann, Vincent R. ; Breuning, Matthias ; Höcker, Birte:
An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host.
In: ChemBioChem. Vol. 22 (2021) Issue 9 . - pp. 1573-1577.
ISSN 1439-7633
DOI der Verlagsversion: https://doi.org/10.1002/cbic.202000880

Kröger, Pascal ; Shanmugaratnam, Sooruban ; Scheib, Ulrike ; Höcker, Birte:
Fine-tuning spermidine binding modes in the putrescine binding protein PotF.
In: Journal of Biological Chemistry. Vol. 297 (2021) Issue 6 . - No. 101419.
ISSN 0021-9258
DOI der Verlagsversion: https://doi.org/10.1016/j.jbc.2021.101419

Ferruz, Noelia ; Michel, Florian ; Lobos, Francisco ; Schmidt, Steffen ; Höcker, Birte:
Fuzzle 2.0 : Ligand Binding in Natural Protein Building Blocks.
In: Frontiers in Molecular Biosciences. Vol. 8 (2021) . - No. 715972.
ISSN 2296-889X
DOI der Verlagsversion: https://doi.org/10.3389/fmolb.2021.715972

Menzel, Teresa ; Weigert, Sebastian ; Gagsteiger, Andreas ; Eich, Yannik ; Sittl, Sebastian ; Papastavrou, Georg ; Ruckdäschel, Holger ; Altstädt, Volker ; Höcker, Birte:
Impact of Enzymatic Degradation on the Material Properties of Poly(Ethylene Terephthalate).
In: Polymers. Vol. 13 (2021) Issue 22 . - No. 3885.
ISSN 2073-4360
DOI der Verlagsversion: https://doi.org/10.3390/polym13223885

Ferruz, Noelia ; Schmidt, Steffen ; Höcker, Birte:
ProteinTools : a toolkit to analyze protein structures.
In: Nucleic Acids Research. Vol. 49 (2021) Issue W1 . - W559-W566.
ISSN 1362-4962
DOI der Verlagsversion: https://doi.org/10.1093/nar/gkab375

2019

You, Weijie:
Activation and inhibition of Sirt6 by small molecules.
Bayreuth , 2019 . - 120 P.
( Doctoral thesis, 2019 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

2018

Lichtenstein, Bruce R. ; Höcker, Birte:
Engineering an AB₅ Protein Carrier.
In: Scientific Reports. Vol. 2018 (23 August 2018) Issue 8 . - No. 12643.
ISSN 2045-2322
DOI der Verlagsversion: https://doi.org/10.1038/s41598-018-30910-y