Microbial repellence properties of engineered spider silk coatings prevent biofilm formation of opportunistic bacterial strains

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00005872
URN to cite this document: urn:nbn:de:bvb:703-epub-5872-9

Title data

Sommer, Christoph ; Bargel, Hendrik ; Raßmann, Nadine ; Scheibel, Thomas:
Microbial repellence properties of engineered spider silk coatings prevent biofilm formation of opportunistic bacterial strains.
In: MRS Communications. Vol. 11 (2021) Issue 3 . - pp. 356-362.
ISSN 2159-6867
DOI der Verlagsversion: https://doi.org/10.1557/s43579-021-00034-y

	Format: PDF Name: Sommer2021_Article_MicrobialRepellencePropertiesO.pdf Version: Published Version Available under License Creative Commons BY 4.0: Attribution
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Abstract

Bacterial infections are well recognised to be one of the most important current public health problems. Inhibiting adhesion of microbes on biomaterials is one approach for preventing inflammation. Coatings made of recombinant spider silk proteins based on the consensus sequence of Araneus diadematus dragline silk fibroin 4 have previously shown microbe-repellent properties. Concerning silicone implants, it has been further shown that spider silk coatings are effective in lowering the risk of capsular fibrosis. Here, microbial repellence tests using four opportunistic infection-related strains revealed additional insights into the microbe-repellent properties of spider silk-coated implants, exemplarily shown for silicone surfaces.

Further data

Item Type:	Article in a journal
Keywords:	Structural; Protein; Biofilm; Biomaterial; Scanning electron microscopy
DDC Subjects:	500 Science > 540 Chemistry 600 Technology, medicine, applied sciences 600 Technology, medicine, applied sciences > 620 Engineering
Institutions of the University:	Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry II - Interfaces and Nanoanalytics Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Chair Biomaterials Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel Profile Fields Profile Fields > Advanced Fields Profile Fields > Advanced Fields > Polymer and Colloid Science Profile Fields > Advanced Fields > Advanced Materials Profile Fields > Advanced Fields > Molecular Biosciences Profile Fields > Emerging Fields Profile Fields > Emerging Fields > Food and Health Sciences Research Institutions Research Institutions > Central research institutes Research Institutions > Central research institutes > Bayreuth Center for Material Science and Engineering - BayMAT
Language:	English
Originates at UBT:	Yes
URN:	urn:nbn:de:bvb:703-epub-5872-9
Date Deposited:	28 Oct 2021 08:49
Last Modified:	28 Oct 2021 08:49
URI:	https://epub.uni-bayreuth.de/id/eprint/5872

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