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Microbial repellence properties of engineered spider silk coatings prevent biofilm formation of opportunistic bacterial strains

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00005872
URN to cite this document: urn:nbn:de:bvb:703-epub-5872-9

Title data

Sommer, Christoph ; Bargel, Hendrik ; Raßmann, Nadine ; Scheibel, Thomas:
Microbial repellence properties of engineered spider silk coatings prevent biofilm formation of opportunistic bacterial strains.
In: MRS Communications. Vol. 11 (2021) Issue 3 . - pp. 356-362.
ISSN 2159-6867
DOI der Verlagsversion: https://doi.org/10.1557/s43579-021-00034-y

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Abstract

Bacterial infections are well recognised to be one of the most important current public health problems. Inhibiting adhesion of microbes on biomaterials is one approach for preventing inflammation. Coatings made of recombinant spider silk proteins based on the consensus sequence of Araneus diadematus dragline silk fibroin 4 have previously shown microbe-repellent properties. Concerning silicone implants, it has been further shown that spider silk coatings are effective in lowering the risk of capsular fibrosis. Here, microbial repellence tests using four opportunistic infection-related strains revealed additional insights into the microbe-repellent properties of spider silk-coated implants, exemplarily shown for silicone surfaces.

Further data

Item Type: Article in a journal
Keywords: Structural; Protein; Biofilm; Biomaterial; Scanning electron microscopy
DDC Subjects: 500 Science > 540 Chemistry
600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Institutions of the University: Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry II
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Emerging Fields
Profile Fields > Emerging Fields > Food and Health Sciences
Research Institutions
Research Institutions > Research Centres
Research Institutions > Research Centres > Bayreuth Center for Material Science and Engineering - BayMAT
Language: English
Originates at UBT: Yes
URN: urn:nbn:de:bvb:703-epub-5872-9
Date Deposited: 28 Oct 2021 08:49
Last Modified: 28 Oct 2021 08:49
URI: https://epub.uni-bayreuth.de/id/eprint/5872

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