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URN to cite this document: urn:nbn:de:bvb:703-epub-8987-9
Title data
Kitana, Waseem ; Apsite, Indra ; Ionov, Leonid:
3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications : Possibilities and Limitations.
In: Advanced Functional Materials.
(14 April 2025)
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- 2500450.
ISSN 1616-3028
DOI der Verlagsversion: https://doi.org/10.1002/adfm.202500450
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Project information
| Project title: |
Project's official title Project's id Künstlich hergestelltes Skelettmuskelgewebe für die Modellierung primärer mitochondrialer Myopathien 409232653 TRR 225: Von den Grundlagen der Biofabrikation zu funktionalen Gewebemodellen 326998133 Open Access Publizieren No information |
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| Project financing: |
Deutsche Forschungsgemeinschaft |
Abstract
Biofabrication is an emerging interdisciplinary field of engineering that aims to develop technologies for applications in tissue engineering and regenerative medicine. A progressing biofabrication technology is 3D (bio) printing (3DBP), which allows for controlled spatial deposition of cell-laden bioinks in a layer-by-layer approach to fabricate biologically active constructs. Although 3DBP can create some biologically relevant structures, it uses hydrogels, which are isotropic in nature and do not provide sufficient mechanical properties to reconstruct many tissues, such as cartilage, bone, and skin. Additionally, hydrogels alone do not replicate the complex hierarchical buildup of native tissue extracellular matrix (ECM), which contains both gel-like and fibrous components. Replicating native tissue's structure both mechanically and biologically by incorporating fibers would result in enhanced biological performance. This is possible by integrating biofabrication technologies such as 3DBP and fiber fabrication techniques. Thus, harnessing the strengths of each technique and eliminating their limitations. This will enable the fabrication of hybrid 3D constructs with multiscale hierarchy and enhanced mechanical and biological performance comparable to native tissue. This review aims to highlight attempts to combine fiber fabrication methods with 3DBP for tissue engineering applications. Additionally, different fiber fabrication techniques are discussed, showcasing their limitations and possible integration with 3DBP.
Further data
| Item Type: | Article in a journal |
|---|---|
| DDC Subjects: | 500 Science > 570 Life sciences, biology 600 Technology, medicine, applied sciences > 600 Technology 600 Technology, medicine, applied sciences > 610 Medicine and health 600 Technology, medicine, applied sciences > 620 Engineering 600 Technology, medicine, applied sciences > 670 Manufacturing |
| Institutions of the University: | Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Professor Biofabrication Faculties > Faculty of Engineering Science > Professor Biofabrication > Professor Biofabrication - Univ.-Prof. Dr. Leonid Ionov Research Institutions > Affiliated Institutes > Bavarian Polymer Institute (BPI) Research Institutions Research Institutions > Affiliated Institutes |
| Language: | English |
| Originates at UBT: | Yes |
| URN: | urn:nbn:de:bvb:703-epub-8987-9 |
| Date Deposited: | 16 Mar 2026 12:56 |
| Last Modified: | 16 Mar 2026 12:56 |
| URI: | https://epub.uni-bayreuth.de/id/eprint/8987 |
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