4D-Printable Photocrosslinkable Polyurethane-Based Inks for Tissue Scaffold and Actuator Applications

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00007455
URN to cite this document: urn:nbn:de:bvb:703-epub-7455-4

Title data

Goodarzi Hosseinabadi, Hossein ; Biswas, Arpan ; Bhusal, Anant ; Yousefinejad, Ali ; Lall, Aastha ; Zimmermann, Wolfram-Hubertus ; Miri, Amir K. ; Ionov, Leonid:
4D-Printable Photocrosslinkable Polyurethane-Based Inks for Tissue Scaffold and Actuator Applications.
In: Small. Vol. 20 (2024) Issue 6 . - 2306387.
ISSN 1613-6829
DOI der Verlagsversion: https://doi.org/10.1002/smll.202306387

	Format: PDF Name: Small - 2023 - Goodarzi Hosseinabadi - 4D‐Printable Photocrosslinkable Polyurethane‐Based Inks for Tissue Scaffold and.pdf Version: Published Version Available under License Creative Commons BY 4.0: Attribution
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Project information

Project financing:	Alexander von Humboldt-Stiftung Fellowship AvH DFG IO 68/16-1, IO 68/17-1, TRR 225 project number 326998133 subproject A08 VW (Experiment!)

Abstract

4D printing recently emerges as an exciting evolution of conventional 3D printing, where a printed construct can quickly transform in response to a specific stimulus to switch between a temporary variable state and an original state. In this work, a photocrosslinkable polyethylene–glycol polyurethane ink is synthesized for light-assisted 4D printing of smart materials. The molecular weight distribution of the ink monomers is tunable by adjusting the copolymerization reaction time. Digital light processing (DLP) technique is used to program a differential swelling response in the printed constructs after humidity variation. Bioactive microparticles are embedded into the ink and the improvement of biocompatibility of the printed constructs is demonstrated for tissue engineering applications. Cell studies reveal above 90% viability in 1 week and ≈50% biodegradability after 4 weeks. Self-folding capillary scaffolds, dynamic grippers, and film actuators are made and activated in a humid environment. The approach offers a versatile platform for the fabrication of complex constructs. The ink can be used in tissue engineering and actuator applications, making the ink a promising avenue for future research.

Further data

Item Type:	Article in a journal
Keywords:	4D printing; bi-modal molecular weight distribution; biocompatiblepolyurethane ink; hydrogel digital light processing (DLP) printing
DDC Subjects:	500 Science > 540 Chemistry 600 Technology, medicine, applied sciences > 600 Technology 600 Technology, medicine, applied sciences > 620 Engineering 600 Technology, medicine, applied sciences > 670 Manufacturing
Institutions of the University:	Faculties > Faculty of Engineering Science > Professor Biofabrication > Professor Biofabrication - Univ.-Prof. Dr. Leonid Ionov Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Professor Biofabrication
Language:	English
Originates at UBT:	Yes
URN:	urn:nbn:de:bvb:703-epub-7455-4
Date Deposited:	12 Feb 2024 06:39
Last Modified:	12 Feb 2024 06:39
URI:	https://epub.uni-bayreuth.de/id/eprint/7455

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