URN to cite this document: urn:nbn:de:bvb:703-epub-4826-9
Title data
Rodriguez-Garcia, Ruddi ; Mell, Michael ; Lopez-Montero, Ivan ; Netzel, Jeanette ; Hellweg, Thomas ; Monroy, Francisco:
Polymersomes : smart vesicles of tunable rigidity and permeability.
In: Soft Matter.
Vol. 7
(2011)
Issue 4
.
- pp. 1532-1542.
ISSN 1744-6848
DOI der Verlagsversion: https://doi.org/10.1039/c0sm00823k
Abstract
We report an experimental study on the mechanical and permeability properties of giant polymersomes made of diblock (PBD-PEO) and triblock (PEO-PPO-PEO) copolymers. These polymer amphiphiles bear the architecture and macromolecular dimensions adequate for assembling stable flat bilayers with a different hydrophobicity. In the highly hydrophobic case (PBD-PEO) an extremely compact membrane is formed, resulting in rigid polymersomes which represent a permeability barrier against solute transport across. In the case of water soluble PEO-PPO-PEO triblock copolymers, the bilayer structure is less stable in favour of the micellar state; therefore giant vesicles can be solely formed at large PPO contents. These cases (Pluronicsregistered sign L121 and its mixtures with P85 and P105) are characterised by a much lower chain entangling than highly hydrophobic membranes{,} their polymersomes being softer than those based on PBD-PEO. Pluronic-based polymersomes are also found to be highly permeable to hydrophilic solutes{,} even remaining undamaged in the case of an extreme osmotic shock. This high permeability together with their high flexibility endows Pluronics polymersomes smart core/shell properties ideal to catch large biomolecules inside and able to resist under osmotic and mechanical stresses.
Further data
Item Type: | Article in a journal |
---|---|
Additional notes (visible to public): | ISI:000287091600035 |
DDC Subjects: | 500 Science > 530 Physics |
Institutions of the University: | Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Former Professors > Chair Crystallography - Univ.-Prof. Dr. Sander van Smaalen Faculties Faculties > Faculty of Mathematics, Physics und Computer Science Faculties > Faculty of Mathematics, Physics und Computer Science > Group Material Sciences Faculties > Faculty of Mathematics, Physics und Computer Science > Group Material Sciences > Chair Crystallography Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Former Professors |
Language: | English |
Originates at UBT: | Yes |
URN: | urn:nbn:de:bvb:703-epub-4826-9 |
Date Deposited: | 28 Aug 2020 05:47 |
Last Modified: | 28 Aug 2020 05:47 |
URI: | https://epub.uni-bayreuth.de/id/eprint/4826 |