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Interactions of cells with silk surfaces

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00004761
URN zum Zitieren der Version auf EPub Bayreuth: urn:nbn:de:bvb:703-epub-4761-8

Titelangaben

Leal-Egaña, Aldo ; Scheibel, Thomas:
Interactions of cells with silk surfaces.
In: Journal of Materials Chemistry. Bd. 22 (2012) Heft 29 . - S. 14330-14336.
ISSN 0959-9428
DOI der Verlagsversion: https://doi.org/10.1039/c2jm31174g

Angaben zu Projekten

Projektfinanzierung: U.S.Army Research Office (grant number W911NF-0810284).

Abstract

Polymers are often employed in tissue engineering to replace damaged extracellular matrix (ECM). During the last few decades silk proteins have been extensively investigated concerning their use as biopolymers for the generation of biocompatible, artificial scaffolds. Including the low or absence of immune-response and lack of cell toxicity, silk proteins present interesting properties useful for tissue engineering and organ repair. Since cell–matrix interactions define the behaviour of cells and posterior graft integration, this review is focused on the influence of surface properties of silk scaffolds (wettability, charge, elasticity and biodegradability) on the biological activity (adhesion, proliferation and/or migration) of cells cultured thereon. Further, it is highlighted how the origin of silk proteins (natural source, regenerated or recombinantly produced), as well as the scaffold morphology and its treatment/post-treatment influence the scaffold surface properties in the context of biomedical applications.

Weitere Angaben

Publikationsform: Artikel in einer Zeitschrift
Zusätzliche Informationen (öffentlich sichtbar): ISI:000305966200002
Themengebiete aus DDC: 600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften
Institutionen der Universität: Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Biomaterialien > Lehrstuhl Biomaterialien - Univ.-Prof. Dr. Thomas Scheibel
Fakultäten
Fakultäten > Fakultät für Ingenieurwissenschaften
Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Biomaterialien
Sprache: Englisch
Titel an der UBT entstanden: Ja
URN: urn:nbn:de:bvb:703-epub-4761-8
Eingestellt am: 04 Sep 2020 05:02
Letzte Änderung: 04 Sep 2020 05:03
URI: https://epub.uni-bayreuth.de/id/eprint/4761

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