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Biotechnological production of the mussel byssus derived collagen preColD

Title data

Golser, Adrian V. ; Scheibel, Thomas:
Biotechnological production of the mussel byssus derived collagen preColD.
In: RSC Advances. (2017) Issue 61 .
ISSN 2046-2069
DOI der Verlagsversion: https://doi.org/10.1039/c7ra04515h

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Name:	c7ra04515h.pdf
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Abstract

Marine mussels adhere to substrates within the intertidal zone by means of a bundle of threads called the mussel byssus which contains several collagen-like proteins responsible for the mechanical properties of the fibers. Here, we demonstrate the biotechnological production of one of three identified byssus collagens, preColD, from Mytilus galloprovincialis using Pichia pastoris as the expression host. Previously detected structural features of natural preColD, such as collagen triple helix formation, could also be detected in the recombinant preColD, even in the absence of hydroxylation of proline or tyrosine residues.

Further data

Item Type:	Article in a journal
DDC Subjects:	600 Technology, medicine, applied sciences 600 Technology, medicine, applied sciences > 620 Engineering
Institutions of the University:	Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Chair Biomaterials Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel Profile Fields Profile Fields > Advanced Fields Profile Fields > Advanced Fields > Polymer and Colloid Science Profile Fields > Advanced Fields > Advanced Materials Profile Fields > Advanced Fields > Molecular Biosciences Profile Fields > Emerging Fields Profile Fields > Emerging Fields > Food and Health Sciences Research Institutions Research Institutions > Central research institutes Research Institutions > Central research institutes > Bayreuth Center for Material Science and Engineering - BayMAT
Language:	English
Originates at UBT:	Yes
Date Deposited:	20 Aug 2018 09:36
Last Modified:	29 Jun 2020 10:52
URI:	https://epub.uni-bayreuth.de/id/eprint/3792

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