Centriole disengagement : What are the relative contributions of Cohesin versus Pericentrin inactivation?

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00008504
URN to cite this document: urn:nbn:de:bvb:703-epub-8504-2

Title data

Kahlen, Philip:
Centriole disengagement : What are the relative contributions of Cohesin versus Pericentrin inactivation?
Bayreuth , 2025 . - 130 P.
( Doctoral thesis, 2024 , University of Bayreuth, Faculty of Biology, Chemistry and Earth Sciences)

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Abstract

Centriole disengagement is defined as the spatial separation of centrioles during late mitosis and is thought to act as a licensing step for their duplication in the following cell cycle. This work is focused on the relative contribution of proteolytical inactivation of centrosomal Cohesin and Pericentrin to centriole disengagement.

Abstract in another language

Die Entkopplung der Zentriolen ist definiert als deren räumliche Trennung in später Mitose und dient als Lizenzierungsschritt für die Duplikation im folgenden Zellzyklus. In der vorliegenden Arbeit wird untersucht, wie und in welchen Anteilen die proteolytische Inaktivierung von Kohäsin und Perizentrin zur Entkopplung der Zentriolen beitragen.

Further data

Item Type:	Doctoral thesis (No information)
Keywords:	Centrosomes; Centriole disengagement; Cohesin; Pericentrin; Mitosis
DDC Subjects:	500 Science
Institutions of the University:	Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Genetics > Chair Genetics - Univ.-Prof. Dr. Olaf Stemmann Graduate Schools > University of Bayreuth Graduate School Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Genetics Graduate Schools
Language:	English
Originates at UBT:	Yes
URN:	urn:nbn:de:bvb:703-epub-8504-2
Date Deposited:	25 Jun 2025 10:00
Last Modified:	25 Jun 2025 10:01
URI:	https://epub.uni-bayreuth.de/id/eprint/8504

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