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Speckle-Tracking Analysis of the Right and Left Heart after Peak Exercise in Healthy Subjects with Type 1 Diabetes: An Explorative Analysis of the AppEx Trial

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00007615
URN zum Zitieren der Version auf EPub Bayreuth: urn:nbn:de:bvb:703-epub-7615-3

Titelangaben

Zimmermann, Paul ; Schierbauer, Janis ; Kopf, Niklas ; Sourij, Harald ; Oliver, Nick ; Aberer, Felix ; Wachsmuth, Nadine B. ; Moser, Othmar:
Speckle-Tracking Analysis of the Right and Left Heart after Peak Exercise in Healthy Subjects with Type 1 Diabetes: An Explorative Analysis of the AppEx Trial.
In: Journal of Cardiovascular Development and Disease. Bd. 10 (2023) Heft 11 .
ISSN 2308-3425
DOI der Verlagsversion: https://doi.org/10.3390/jcdd10110467

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Angaben zu Projekten

Projekttitel:
Offizieller Projekttitel
Projekt-ID
Outlook to the next 100 years of insulin: Innovative insulin delivery and monitoring systems
Ohne Angabe
Open Access Publizieren
Ohne Angabe

Projektfinanzierung: European Foundation for the Study of Diabetes

Abstract

In eight healthy participants with Type 1 diabetes (T1D) exercise-related dynamic cardiac remodeling was analyzed by performing two-dimensional echocardiography, including deformation analysis of the left-ventricular (LV) global longitudinal strain (LV-GLS), and the deformation pattern of the left atrium (LA) and right ventricle (RV) at rest and post-peak performance on a bicycle. The feasibility echocardiographic speckle-tracking analysis was performed on eight asymptomatic participants with T1D (n = 8, male n = 5, age: 23–65 years). The obtained echocardiographic data were compared for various echocardiographic parameters at rest and post exercise. Across our participating T1D individuals no structural echocardiographic abnormalities of concern could be revealed. All participating T1D subjects showed preserved contractile reserve of the LV and no significant diastolic dysfunction. Significant differences were found for the phasic LA contractile strain pattern at rest and post exercise (p < 0.001), whereby the dynamic RV (p = 0.5839 and p = 0.7419) and LV strain pattern (p = 0.5952) did not reveal significant differences in comparison to resting conditions. This descriptive secondary outcome analysis describes preserved contractile reserve of the LV and elucidates dynamic modification of the phasic LA contractile deformation pattern in asymptomatic T1D individuals after exhaustive exercise on a bicycle.

Weitere Angaben

Publikationsform: Artikel in einer Zeitschrift
Keywords: echocardiography; strain analysis; type 1 diabetes; cardiac remodeling; diabetic
cardiomyopathy
Themengebiete aus DDC: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
Institutionen der Universität: Fakultäten > Kulturwissenschaftliche Fakultät > Institut für Sportwissenschaft > Lehrstuhl Exercise Physiology > Lehrstuhl Exercise Physiology - Univ.-Prof. Dr. Othmar Moser
Fakultäten
Fakultäten > Kulturwissenschaftliche Fakultät
Fakultäten > Kulturwissenschaftliche Fakultät > Institut für Sportwissenschaft
Fakultäten > Kulturwissenschaftliche Fakultät > Institut für Sportwissenschaft > Lehrstuhl Exercise Physiology
Sprache: Englisch
Titel an der UBT entstanden: Ja
URN: urn:nbn:de:bvb:703-epub-7615-3
Eingestellt am: 21 Mrz 2024 09:19
Letzte Änderung: 21 Mrz 2024 09:20
URI: https://epub.uni-bayreuth.de/id/eprint/7615

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