URN to cite this document: urn:nbn:de:bvb:703-epub-7477-5
Title data
Fertig, Robin ; Leowsky-Künstler, Felix ; Irrgang, Torsten ; Kempe, Rhett:
Rational design of N-heterocyclic compound classes via regenerative cyclization of diamines.
In: Nature Communications.
Vol. 14
(2023)
.
- 595.
ISSN 2041-1723
DOI der Verlagsversion: https://doi.org/10.1038/s41467-023-36220-w
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Abstract
The discovery of reactions is a central topic in chemistry and especially interesting if access to compound classes, which have not yet been synthesized, is permitted. N-Heterocyclic compounds are very important due to their numerous applications in life and material science. We introduce here a consecutive three-component reaction, classes of N-heterocyclic compounds, and the associated synthesis concept (regenerative cyclisation). Our reaction starts with a diamine, which reacts with an amino alcohol via dehydrogenation, condensation, and cyclisation to form a new pair of amines that undergoes ring closure with an aldehyde, carbonyldiimidazole, or a dehydrogenated amino alcohol. Hydrogen is liberated in the first reaction step and the dehydrogenation catalyst used is based on manganese.
Further data
Item Type: | Article in a journal |
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DDC Subjects: | 500 Science 500 Science > 540 Chemistry |
Institutions of the University: | Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Inorganic Chemistry II Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Inorganic Chemistry II > Chair Inorganic Chemistry II - Univ.-Prof. Dr. Rhett Kempe |
Language: | English |
Originates at UBT: | Yes |
URN: | urn:nbn:de:bvb:703-epub-7477-5 |
Date Deposited: | 20 Feb 2024 07:40 |
Last Modified: | 20 Feb 2024 07:42 |
URI: | https://epub.uni-bayreuth.de/id/eprint/7477 |