Long‐Term Stability, Biocompatibility, and Magnetization of Suspensions of Isolated Bacterial Magnetosomes

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00007288
URN to cite this document: urn:nbn:de:bvb:703-epub-7288-6

Title data

Mickoleit, Frank ; Jörke, Cornelia ; Richter, Reinhard ; Rosenfeldt, Sabine ; Markert, Simon ; Rehberg, Ingo ; Schenk, Anna ; Bäumchen, Oliver ; Schüler, Dirk ; Clement, Joachim H.:
Long‐Term Stability, Biocompatibility, and Magnetization of Suspensions of Isolated Bacterial Magnetosomes.
In: Small. Vol. 19 (2023) Issue 19 . - 2206244.
ISSN 1613-6829
DOI der Verlagsversion: https://doi.org/10.1002/smll.202206244

	Format: PDF Name: Small - 2023 - Mickoleit - Long‐Term Stability Biocompatibility and Magnetization of Suspensions of Isolated Bacterial.pdf Version: Published Version Available under License Creative Commons BY 4.0: Attribution
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Abstract

Magnetosomes are magnetic nanoparticles biosynthesized by magnetotactic bacteria. Due to a genetically strictly controlled biomineralization process, the ensuing magnetosomes have been envisioned as agents for biomedical and clinical applications. In the present work, different stability parameters of magnetosomes isolated from Magnetospirillum gryphiswaldense upon storage in suspension (HEPES buffer, 4 °C, nitrogen atmosphere) for one year in the absence of antibiotics are examined. The magnetic potency, measured by the saturation magnetization of the particle suspension, drops to one-third of its starting value within this year—about ten times slower than at ambient air and room temperature. The particle size distribution, the integrity of the surrounding magnetosome membrane, the colloidal stability, and the biocompatibility turn out to be not severely affected by long-term storage.

Further data

Item Type:	Article in a journal
Keywords:	biocompatibility; long-term stability; magnetic nanoparticles; magnetization; magnetosomes
DDC Subjects:	500 Science > 530 Physics
Institutions of the University:	Faculties Faculties > Faculty of Mathematics, Physics und Computer Science Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Former Professors Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics V Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Former Professors > Chair Experimental Physics V - Univ.-Prof. Dr. Ingo Rehberg Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics V > Chair Experimental Physics V - Univ.-Prof. Dr. Oliver Bäumchen Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry IV - Bioinspirierte Kolloidsysteme und Streumethoden > Chair Physical Chemistry IV - Bioinspirierte Kolloidsysteme und Streumethoden - Univ.-Prof. Dr. Anna Schenk Profile Fields Profile Fields > Advanced Fields Profile Fields > Advanced Fields > Nonlinear Dynamics Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry IV - Bioinspirierte Kolloidsysteme und Streumethoden
Language:	English
Originates at UBT:	Yes
URN:	urn:nbn:de:bvb:703-epub-7288-6
Date Deposited:	08 Nov 2023 08:18
Last Modified:	08 Nov 2023 08:19
URI:	https://epub.uni-bayreuth.de/id/eprint/7288

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