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Zwitterionic Polymer Brushes and Core-Shell Particles Based thereon for Control of Biofouling

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00007278
URN to cite this document: urn:nbn:de:bvb:703-epub-7278-0

Title data

Kopsch, Fabian ; Drechsler, Astrid ; Priebs, Martina ; Caspari, Anja ; Müller, Anett ; Lentz, Sarah ; Friedrichs, Jens ; Synytska, Alla:
Zwitterionic Polymer Brushes and Core-Shell Particles Based thereon for Control of Biofouling.
In: Macromolecular Chemistry and Physics. Vol. 224 (2023) Issue 9 . - 2200454.
ISSN 1521-3935
DOI der Verlagsversion: https://doi.org/10.1002/macp.202200454

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Project information

Project financing: Deutsche Forschungsgemeinschaft

Abstract

Abstract Biofilm formation on material surfaces – biofouling – has a significant economic impact on a wide range of applications and industries. There is a huge need for the prevention of undesired interactions of coatings with proteins, cells, and bacteria in biomaterials, biosensors, and other applications. In this work, the preparation and characterization as well as the comparison of bio-fouling properties of surfaces based on planar zwitterionic polymer brushes made of poly(sulfobetaine methacrylate) P(SBMA-3), poly(carboxybetaine methacrylate) P(CBMA-2), or poly(2-methacryloyloxyethyl phosphorylcholine) P(MPC-2) are reported. Since polymer brushes on planar surfaces have disadvantages with regard to layer stability, industrial scaling, and the coating of complex geometries, nano- and microstructured coatings based on polymer-functionalized core-shell particles are subsequently produced. It is found that coatings based on poly(phosphorylcholine) P(MPC-2) modified particles with a diameter of 100 nm have the lowest bioadhesion compared to other particle sizes and chemical compositions. The particle-based coatings developed can pave the way for developing scalable anti-fouling coatings in the future.

Further data

Item Type: Article in a journal
Keywords: antifouling surfaces; particle coatings; roughness; zwitterionic polymers
DDC Subjects: 600 Technology, medicine, applied sciences > 620 Engineering
Institutions of the University: Research Institutions > Affiliated Institutes > Bavarian Polymer Institute (BPI)
Research Institutions
Research Institutions > Affiliated Institutes
Language: English
Originates at UBT: Yes
URN: urn:nbn:de:bvb:703-epub-7278-0
Date Deposited: 03 Nov 2023 09:12
Last Modified: 03 Nov 2023 09:13
URI: https://epub.uni-bayreuth.de/id/eprint/7278

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