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Miniaturized magnetic stir bars for controlled agitation of aqueous microdroplets

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00005553
URN to cite this document: urn:nbn:de:bvb:703-epub-5553-8

Title data

Gires, Pierre-Yves ; Thampi, Mithun ; Weiss, Matthias:
Miniaturized magnetic stir bars for controlled agitation of aqueous microdroplets.
In: Scientific Reports. Vol. 10 (2 July 2020) Issue 1 . - No. 10911.
ISSN 2045-2322
DOI der Verlagsversion: https://doi.org/10.1038/s41598-020-67767-z

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Project financing: VolkswagenStiftung

Abstract

Controlled stirring of tiny volumes of aqueous fluids is of particular importance in the life sciences, e.g. in the context of microfluidic and lab-on-chip applications. Local stirring not only accelerates fluid mixing and diffusion-limited processes, but it also allows for adding controlled active noise to the fluid. Here we report on the synthesis and characterization of magnetic nano-stir bars (MNBs) with which these features can be achieved in a straightforward fashion. We also demonstrate the applicability of MNBs to cell extract droplets in microfluidic channels and we show that they can introduce active noise to cell extracts as evidenced by altered fluctuations of ensembles of cytoskeletal filaments.

Further data

Item Type: Article in a journal
Keywords: Biophysics; Physical chemistry
DDC Subjects: 500 Science > 530 Physics
500 Science > 570 Life sciences, biology
Institutions of the University: Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics I - Physics of Living Matter > Chair Experimental Physics I - Physics of Living Matter - Univ.-Prof. Dr. Matthias Weiss
Faculties
Faculties > Faculty of Mathematics, Physics und Computer Science
Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics
Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics I - Physics of Living Matter
Language: English
Originates at UBT: Yes
URN: urn:nbn:de:bvb:703-epub-5553-8
Date Deposited: 19 May 2021 08:29
Last Modified: 19 May 2021 08:29
URI: https://epub.uni-bayreuth.de/id/eprint/5553

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