URN to cite this document: urn:nbn:de:bvb:703-epub-6946-1
Title data
Haupt, Sandra ; Niedrist, Tobias ; Sourij, Harald ; Schwarzinger, Stephan ; Moser, Othmar:
The Impact of Exercise on Telomere Length, DNA Methylation and Metabolic Footprints.
In: Cells.
Vol. 11
(2022)
Issue 1
.
- No. 153.
ISSN 2073-4409
DOI der Verlagsversion: https://doi.org/10.3390/cells11010153
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Abstract
Aging as a major risk factor influences the probability of developing cancer, cardiovascular disease and diabetes, amongst others. The underlying mechanisms of disease are still not fully understood, but research suggests that delaying the aging process could ameliorate these pathologies. A key biological process in aging is cellular senescence which is associated with several stressors such as telomere shortening or enhanced DNA methylation. Telomere length as well as DNA methylation levels can be used as biological age predictors which are able to detect excessive acceleration or deceleration of aging. Analytical methods examining aging are often not suitable, expensive, time-consuming or require a high level of technical expertise. Therefore, research focusses on combining analytical methods which have the potential to simultaneously analyse epigenetic, genomic as well as metabolic changes.
Further data
Item Type: | Article in a journal |
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Keywords: | telomere length; DNA methylation; metabolomics; exercise; metabolism |
DDC Subjects: | 600 Technology, medicine, applied sciences > 610 Medicine and health |
Institutions of the University: | Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology > Chair Exercise Physiology - Univ.-Prof. Dr. Othmar Moser Faculties Faculties > Faculty of Cultural Studies Faculties > Faculty of Cultural Studies > Department of Sport Science |
Language: | English |
Originates at UBT: | Yes |
URN: | urn:nbn:de:bvb:703-epub-6946-1 |
Date Deposited: | 04 Apr 2023 08:48 |
Last Modified: | 04 Apr 2023 08:51 |
URI: | https://epub.uni-bayreuth.de/id/eprint/6946 |