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The Impact of Exercise on Telomere Length, DNA Methylation and Metabolic Footprints

DOI zum Zitieren der Version auf EPub Bayreuth: https://doi.org/10.15495/EPub_UBT_00006946
URN to cite this document: urn:nbn:de:bvb:703-epub-6946-1

Title data

Haupt, Sandra ; Niedrist, Tobias ; Sourij, Harald ; Schwarzinger, Stephan ; Moser, Othmar:
The Impact of Exercise on Telomere Length, DNA Methylation and Metabolic Footprints.
In: Cells. Vol. 11 (2022) Issue 1 . - No. 153.
ISSN 2073-4409
DOI der Verlagsversion: https://doi.org/10.3390/cells11010153

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Abstract

Aging as a major risk factor influences the probability of developing cancer, cardiovascular disease and diabetes, amongst others. The underlying mechanisms of disease are still not fully understood, but research suggests that delaying the aging process could ameliorate these pathologies. A key biological process in aging is cellular senescence which is associated with several stressors such as telomere shortening or enhanced DNA methylation. Telomere length as well as DNA methylation levels can be used as biological age predictors which are able to detect excessive acceleration or deceleration of aging. Analytical methods examining aging are often not suitable, expensive, time-consuming or require a high level of technical expertise. Therefore, research focusses on combining analytical methods which have the potential to simultaneously analyse epigenetic, genomic as well as metabolic changes.

Further data

Item Type: Article in a journal
Keywords: telomere length; DNA methylation; metabolomics; exercise; metabolism
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
Institutions of the University: Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology
Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology > Chair Exercise Physiology - Univ.-Prof. Dr. Othmar Moser
Faculties
Faculties > Faculty of Cultural Studies
Faculties > Faculty of Cultural Studies > Department of Sport Science
Language: English
Originates at UBT: Yes
URN: urn:nbn:de:bvb:703-epub-6946-1
Date Deposited: 04 Apr 2023 08:48
Last Modified: 04 Apr 2023 08:51
URI: https://epub.uni-bayreuth.de/id/eprint/6946

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