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Biotechnological production of the mussel byssus derived collagen preColD

DOI zum Zitieren dieses Dokuments: https://doi.org/10.1039/c7ra04515h

Title data

Golser, Adrian V. ; Scheibel, Thomas:
Biotechnological production of the mussel byssus derived collagen preColD.
In: RSC Advances. (2017) Issue 61 .
ISSN 2046-2069
DOI: https://doi.org/10.1039/c7ra04515h

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Abstract

Marine mussels adhere to substrates within the intertidal zone by means of a bundle of threads called the mussel byssus which contains several collagen-like proteins responsible for the mechanical properties of the fibers. Here, we demonstrate the biotechnological production of one of three identified byssus collagens, preColD, from Mytilus galloprovincialis using Pichia pastoris as the expression host. Previously detected structural features of natural preColD, such as collagen triple helix formation, could also be detected in the recombinant preColD, even in the absence of hydroxylation of proline or tyrosine residues.

Further data

Item Type: Article in a journal
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Emerging Fields
Profile Fields > Emerging Fields > Food and Health Sciences
Research Institutions
Research Institutions > Research Centres
Research Institutions > Research Centres > Bayreuth Center for Material Science and Engineering - BayMAT
Language: English
Originates at UBT: Yes
Date Deposited: 20 Aug 2018 09:36
Last Modified: 20 Aug 2018 09:36
URI: https://epub.uni-bayreuth.de/id/eprint/3792

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